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1 SAMHSA's National Helpline
› find-help › national-helpline
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2 How Are Tolerance and Withdrawal Related to Drug Abuse?
Tolerance and withdrawal are two pieces that demonstrate that drug abuse is crossing the line and turning into an addiction.
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3 Tolerance and withdrawal (video) - Khan Academy
› science › tolerance-and-...
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4 the difference between tolerance, dependence, and addiction
Feeling withdrawn from daily activities. Inability to stop using a substance. Strong cravings for drugs or alcohol.
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5 Tolerance - Benzodiazepine Information Coalition
The tolerance or “tolerance withdrawal” phenomenon is often how patients initially discover that their benzodiazepine is making them sick.
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6 Tolerance and Withdrawal - Dear Albert
Tolerance and Withdrawal ... The emotional and physical impacts of alcohols manifest during addiction and when people try to get clean. The development of a ...
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7 The Role Tolerance Plays in Addiction - Silvermist Recovery
Tolerance is one stage of the body's development of a physical dependence on a substance. Dependence will result in withdrawal symptoms if a ...
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8 Should tolerance and withdrawal be required for ... - PubMed
Despite the historical importance of tolerance and withdrawal in the substance abuse nomenclature, empirical evaluations of tolerance and withdrawal ...
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9 Neuroadaptation (tolerance & withdrawal) | YouthAOD Toolbox
Tolerance becomes dependence when the absence of the drug produces a negative response: (the user needs to take the drug just to feel “normal” rather than ...
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10 Tolerance, Physical Dependence, and Addiction Explained
Unlike tolerance, which focuses on how much of the substance you need to feel its effect, physical dependence happens when your body starts to ...
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11 Tolerance and Withdrawal Syndrome: Definition - StudySmarter
Tolerance is where the body becomes used to the substance or behaviour, achieving a new normal state. Withdrawal symptoms are where the person stops taking the ...
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12 Tolerance and withdrawal symptoms ... - Wiley Online Library
lates that tolerance and withdrawal symptoms are manda- tory for any behaviour to be considered addictive. In behavioural addictions, tolerance is usually ...
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13 Drug Addiction vs. Tolerance vs. Dependence - Turnbridge
Substance addiction is often associated with symptoms of tolerance, dependence, and withdrawal. Those who are addicted may have built up a tolerance to their ...
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14 Tolerance and Withdrawal from Opiates - Sierra by the Sea
Tolerance occurs when the body tries to neutralize the opiate, or any other psychoactive drug, by a variety of methods. It may speed up the metabolism, ...
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15 Tolerance, Dependence, and Addiction: What Common ...
Dependence means that withdrawal symptoms will occur when the use of a substance is suddenly stopped. Withdrawal symptoms can be physical ...
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16 Drug tolerance: What it is, how to deal with it, and more
People with a drug dependency need to gradually reduce the amount of the drug they take each day to help lessen, limit, or even avoid withdrawal symptoms.
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17 Concepts and controversies regarding tolerance and ...
This functional reaction is similar to a range of withdrawal symptoms and is considered to be a dysfunctional response that maintains substance ...
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18 Understanding Drug Tolerance, Dependence and Addiction
A person will experience withdrawal symptoms (i.e., a sharp increase in pain if withdrawing from painkillers, for example) when they go too long between doses ...
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19 Tolerance, withdrawal, and physical dependency after long-te...,_withdrawal,_and_physical_dependency.79.aspx
Tolerance, physical dependency, and withdrawal can occur after the prolonged administration of any agent used for sedation and analgesia in the PICU population.
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20 Drug Tolerance: What It Is, What to Do About It & More
Tolerance can happen if you've been using a medication or other drug for a while. If you think your body has developed drug tolerance, talk to your doctor. Don' ...
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21 Tolerance and Resistance to Drugs - Merck Manuals
A person may develop tolerance to a drug when the drug is used repeatedly. For instance, when morphine or alcohol is used for a long time, larger and larger ...
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22 Tolerance and withdrawal | MCAT | Khan Academy - YouTube
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23 Drug Tolerance | Dependence and Withdrawal - Alta Centers
What Is Drug Tolerance? ... Drug tolerance is when a person's brain or the body stops responding to recreational or prescription medications in the way it used to ...
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24 Drug tolerance - Wikipedia
Drug tolerance or drug insensitivity is a pharmacological concept describing subjects' reduced reaction to a drug following its repeated use.
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25 Why Tolerance is Important to Understand | Learn More Now
Without it, the body will rebound, suffering the uncomfortable and sometimes dangerous effects of withdrawal. When this stage has been reached, the tolerance ...
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26 What Is Addiction? |
Tolerance, which means your body becomes used to a substance and needs more of it to feel its effects. Physical withdrawal and other ...
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27 Preliminary Evidence that Tolerance and ... - Springer Link
Tolerance refers to the tendency to need more and more of an addictive substance to achieve the same desired effect [15, 16]. Withdrawal refers ...
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28 What's the Difference Between Tolerance, Dependence, and ...
Just because tolerance is developed does not mean that a person is addicted to a substance. It just means that the current level of the drug is no longer ...
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29 Opioid Tolerance and Withdrawal - PrairieShore Pain Center
Opioid tolerance may develop after some time as your body gets used to the opioid medicine. The opioid may not seem to provide the same amount of pain relief ...
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30 tolerance, withdrawal, dependence, and addiction Flashcards
tolerance. adaptation of the body to a drug, resulting in a lessening of the effects of a drug · cross tolerance · pharmacokinetic tolerance · pharmacodynamic ...
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31 6.11 Tolerance, dependence and withdrawal
The evidence suggests a weak relationship between nicotine tolerance and dependence. However, there is a stronger association between withdrawal effects (e.g., ...
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32 What Is A Drug Tolerance? - The Recovery Village
Lean about tolerance, a person's diminished response to taking a drug or alcohol. Tolerance builds up by repeated use of a drug or alcohol ...
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33 Substance Abuse / Chemical Dependency
Tolerance to or need for increased amounts of the drug to get an effect. Withdrawal symptoms that happen if you decrease or stop using the drug that you find ...
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34 Tolerance, Dependence, and Addiction
Tolerance can be a warning sign that someone has an addiction, ... experiencing physical tolerance or the withdrawal symptoms that indicate ...
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35 Tolerance and Withdrawal Issues with Sedation
occurrence of tolerance and withdrawal in the most commonly used sedatives in critically ill patients. Tolerance is defined as a progressive reduction in.
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1. Tolerance to a drug is defined as the failure of a steady dose of the drug over time, to sustain the desired pharmacological effect, i.e., the need ...
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37 Fundamentals of Addiction: Key Concepts in Addiction - CAMH
Tolerance and withdrawal increase the addictive potential of a drug by making it difficult for a person to stop using it without experiencing discomfort.
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38 A Primer on Psychiatric Drug Dependence, Tolerance and ...
In this Primer we explain psychiatric drug-induced dependence, tolerance, and withdrawal. We examine why these phenomena occur, how they develop over time ...
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39 Withdrawal and Tolerance Phenomenon ... - Taylor and Francis
This study compared tolerance and withdrawal features in samples of gamblers, alcoholics and gamblers who also met criteria for alcohol dependence. In contrast ...
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40 The Diagnostic Criteria for Substance Use Disorders (Addiction)
For many people, tolerance and withdrawal are the classic indicators of advanced addiction. As such, these are particularly important concepts. This criterion ...
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41 tolerance | physiology - Encyclopedia Britannica
cocaine. In drug use: Physiological effects of addiction. Tolerance is a physiological phenomenon that requires the individual to use more and more of the drug ...
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42 LSD Tolerance: How Long It Takes to Develop
Withdrawal Symptoms When Detoxing From a Tolerance to LSD ... Since LSD does not create a strong chemical dependency to the degree that many other drugs do. Drugs ...
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43 Addiction, Dependence, and Tolerance to Pain Medication
Physical dependence is evident when someone develops a tolerance to a drug or if one would experience withdrawal symptoms from stopping the ...
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44 "Repeated Zolpidem Treatment Effects on Sedative Tolerance ...
D. Keywords. Zolpidem, Tolerance, Sedative, Withdrawal, Hypnotic, GABAA receptor. Abstract. Zolpidem and ...
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45 Should tolerance and withdrawal be required ... - APA PsycNet
Assessed the historical importance of tolerance and withdrawal in the substance abuse nomenclature. Based on data from 521 Ss (mean age 35.7 yrs) from a ...
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46 Neurobiology and principles of addiction and tolerance
Tolerance and withdrawal. For many drugs of abuse, continual drug use results in tolerance. This is particularly evident for alcohol and opiates, ...
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47 Drug Tolerance Definition Psychology
The state of physical dependence is revealed by withdrawing the drug and noting the occurrence of withdrawal symptoms. Longer-acting drugs tend to produce less ...
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48 Tolerance and Withdrawal From Prolonged Opioid Use in ...
Opioid tolerance was identified from a retrospective chart review in neonates,31 which showed fivefold increases in fentanyl infusions coupled ...
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49 Medline ® Abstract for Reference 166 of 'Prevention and ...
RESULTS Mechanisms of opioid-induced hyperalgesia and tolerance suggest important drug- and patient-related risk factors that lead to tolerance and withdrawal.
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50 Tolerance, dependency, and withdrawal | Musculoskeletal Key
Tolerance is a decrease in a drug's effect over time, generally with the need to increase the dose to achieve the same effect. Tolerance is ...
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51 What do tolerance and withdrawal mean? - Papertrell
What do tolerance and withdrawal mean? ... When people develop tolerance, they have become desensitized to the drug and require more and more of the substance to ...
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52 Physical & Psychological Addiction - Footprints to Recovery
People who experience withdrawal symptoms always develop some level of tolerance to the drug first. Withdrawal symptoms signify physical dependence on the ...
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53 The Neurobiology of Substance Use, Misuse, and Addiction
This is known as tolerance, and it reflects the way that the brain maintains balance and adjusts to a “new normal”—the frequent presence of the substance.
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54 Valium Tolerance: How to Know if You're Using too Much
It's routinely used to treat symptoms of anxiety and occasionally administered to those going through alcohol withdrawal. Unfortunately, despite its multi- ...
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55 Understanding the Difference Between Tolerance ... - Alta Loma
When discussing dependence, the term refers to the withdrawal symptoms that occur when a person ceases the use of drugs or alcohol. Symptoms ...
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56 What Is Drug Tolerance? Is It The Same As Dependence? defines dependence as when a person stops using a drug, their body goes through withdrawal which is a group of physical and ...
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57 Addiction vs. Dependence: Differences In Drug Abuse Terms
Dependence is characterized by the symptoms of tolerance and withdrawal. While it is possible to have a physical dependence without being addicted, ...
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58 Addictionary® – Recovery Research Institute
The ability of one drug to prevent the withdrawal symptoms of one's physical dependence on another. CROSS-TOLERANCE. An individual's tolerance for one drug ...
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59 Withdrawal and tolerance phenomenon in problem gambling
comparing the equivalence of tolerance and withdrawal between gambling and alcohol dependence. The purpose of this study is to compare and contrast ...
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60 The role of classical and instrumental conditioning in drug ...
tolerance; withdrawal symptoms; increasing doses; unsuccessful efforts to cut down intake of the substance; a considerable amount of time spent obtaining or ...
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61 Addiction withdrawal symptoms | healthdirect
What is withdrawal from addiction? ... Withdrawal is the process of cutting out, or cutting back on, addictive substances, such as drugs or alcohol, or behaviours ...
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62 High Tolerance to Alcohol and Drugs -
Tolerance occurs when someone repeatedly uses alcohol or other drugs. Over time, the body no longer reacts to the substance the same way it did the first time ...
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63 Tolerance, Dependence, and Withdrawal - Blog
Tolerance, Dependence, and Withdrawal · Tolerance When a person uses alcohol or drugs repeatedly, the body begins to tolerate the amount ingested ...
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64 Understanding Dependence, Addiction, & Tolerance
Those who are dependent on a substance will experience unpleasant physical withdrawal symptoms when they abruptly reduce or stop use of the drug.
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65 2. Tolerance/Withdrawal - Hook AP Psychology 4B
Tolerance is the weakening effect of a drug that requires the user to take more of the drug to experience a high. When a user takes a larger amount of the ...
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66 Drug Tolerance: The 7 Clinical Types - Recovery First
Acute tolerance allows the brain in part to use areas of the brain not affected by the substance in question, then revert to its normal state ...
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67 Cocaine Addiction: Signs, Effects, & Rehab
... diagnose cocaine addiction, the symptoms of cocaine withdrawal, and the rehab options that are available to help you or your loved one.
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68 Distinguishing risk factors for the onset of cravings, withdrawal ...
Cravings and withdrawal symptoms were tested as predictors of time to tolerance. The cravings variable was not tested in the model for withdrawal symptoms, and ...
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69 Klonopin Tolerance: How to Decrease it Safely | Delphi
The simplest way to know if you have developed a tolerance to a drug is to remove it from your system and see if you experience any withdrawal symptoms.
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70 Opioid tolerance: the clinical perspective
shall discuss clinical aspects of tolerance and the asso- ciated phenomena of dependence, withdrawal and addiction to opioids as they apply to the practice ...
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71 Preliminary Evidence that Tolerance and ... - ResearchGate
Tolerance and withdrawal are core addiction symptoms that have received little attention in the food addiction literature. This review aimed to summarize ...
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72 What is the importance of a counselor having an ... -
A counselor needs to understand the importance of tolerance and withdrawal when working with clients who face substance abuse issues.
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73 Essay Drugs: Tolerance and Withdrawal - 1254 Words | Bartleby
Dependency on a drug then leads to a tolerance to the drug, and before the user knows it, they are addicted. Drugs are like a black hole that vacuums the user ...
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74 The Difference Between Tolerance ... - Florida Recovery Group
Tolerance is one of the diagnostic criteria for a Substance Use Disorder. Tolerance describes needing more of a substance to get the same effect ...
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75 Changes in the development of opioid tolerance on re ... - PLOS
Tolerance was experienced as interacting and co-developing with physical dependence and the symptoms of withdrawal.
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76 Substance Abuse Tolerance and Dependence
A dependence on alcohol results in uncomfortable and potentially fatal withdrawal symptoms with cessation of use. ... The withdrawal symptoms ...
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77 Drug Tolerance: What It Is And Why It's Dangerous
What is the Definition of Drug Tolerance? ... According to the National Institute on Drug Abuse, drug tolerance is “a state in which an organism no longer ...
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78 methyl-dihydro-morphine in the rat
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79 Dopamine efflux during withdrawal from continuous or ...
Daily, intermittent, subcutaneous cocaine injections produce sensitization, while the continuous administration of cocaine produces tolerance to the ...
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80 Opioid Tolerance and Hyperalgesia
Studies have also shown that hyperalgesia caused by fentanyl or heroin, as well as. 204. CHANG et al. Page 7. naloxone-mediated opiate withdrawal, was also ...
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81 Opioid Use Disorder Diagnostic Criteria
The characteristic opioid withdrawal syndrome (refer to Criteria A and B of the ... tolerance and will experience withdrawal on abrupt discontinuation of ...
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82 Tolerance as a Modulator of Drug Response
Development of tolerance to the effects of drugs is a common phenomenon in ... ment of tolerance is often involved in producing withdrawal symptoms.
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83 Substance Addiction: Tolerance and Withdrawal
Tolerance and withdrawal are clear symptoms of substance addiction. If symptoms of tolerance start to appear, then withdrawal symptoms will also ...
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84 Substance-related and addictive disorders - AMBOSS
Tolerance and withdrawal can be normal physiological adaptations. In the absence of other DSM-V criteria, tolerance and withdrawal do not ...
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85 The Difference Between Tolerance, Dependence & Addiction
This is where dependence comes into play. Individuals who dont want to deal with withdrawal symptoms will depend on the substance to relieve ...
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86 About substance use -
On this page: · Substance use spectrum · Tolerance · Dependence · Withdrawal · Prescription drug use and potential harms · Negative effects of ...
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87 What Are The 4 Levels Of Addiction?
They have built up a tolerance to the drug and need increasingly larger amounts to get the same effect. They may also experience withdrawal ...
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88 What Is Cross-Tolerance? Here is Your Comprehensive Guide
Most cases of cross-tolerance occur with drugs in the same class that affects similar areas of the body. If an anti-anxiety drug isn't stabilizing your dopamine ...
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89 Opiate and opioid withdrawal - MedlinePlus
These drugs can cause physical dependence. This means that a person needs to take the drug to prevent withdrawal symptoms. Over time, more of ...
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90 Drug Tolerance: List of Common Medications & Safety Tips
If you use a drug repeatedly, your body can develop drug tolerance. With this condition, you have to take higher doses of the drug—or change ...
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91 Carisoprodol tolerance and precipitated withdrawal — HSC
min of administration. Conclusions: Carisoprodol treatment resulted in tolerance and antagonist-precipitated withdrawal, suggesting it may have ...
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92 DSM-5 Criteria for Substance Use Disorders
Needing more of the substance to get the desired effect — also called tolerance. Developing withdrawal symptoms when not using the substance ...
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93 Understanding Substance Abuse, Addiction, Tolerance ...
Someone abusing a substance can stop taking it, should they decide to do so, without significant withdrawal effects. The person suffering from drug abuse ...
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94 What Are the Dangers of Drugs That Cause Cross-Tolerance?
Cross-tolerance can lead to relapse. While medically managed withdrawal is an important option for safe detox, especially for people who ...
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95 Symptoms of Substance Dependence Associated with Use of ...
... results in tolerance, withdrawal, and compulsive drug-taking behavior. ... use even though {they} tried," and 4) "had withdrawal symptoms, that is, ...
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